AustralieFrV1, Main, Exploration, bibRecord, 000700

Observed benefit and safety of aflibercept in elderly patients with metastatic colorectal cancer: An age-based analysis from the randomized placebo-controlled phase III VELOUR trial.

Identifieur interne : 000700 ( Main/Exploration ); précédent : 000699; suivant : 000701

Observed benefit and safety of aflibercept in elderly patients with metastatic colorectal cancer: An age-based analysis from the randomized placebo-controlled phase III VELOUR trial.

Auteurs : Paul Ruff [Afrique du Sud] ; Eric Van Cutsem [Belgique] ; Radek Lakomy [République tchèque] ; Jana Prausova [République tchèque] ; Guy A. Van Hazel [Australie] ; Vladimir M. Moiseyenko [Russie] ; Karen Soussan-Lazard [France] ; Emmanuelle Dochy [Belgique] ; Emmanuelle Magherini [France] ; Teresa Macarulla [Espagne] ; Demetris Papamichael [Chypre (pays)]

Source :

Journal of geriatric oncology [ 1879-4076 ] ; 2017.

RBID : pubmed:28807738

Abstract

Aflibercept (ziv-aflibercept) significantly improves progression-free (PFS) and overall survival (OS) when added to 5-fluorouracil, leucovorin and irinotecan (FOLFIRI), compared with FOLFIRI alone, in patients with metastatic colorectal cancer previously treated with oxaliplatin-based therapy. This subset analysis of the VELOUR study investigates aflibercept plus FOLFIRI versus placebo plus FOLFIRI according to age.

DOI: 10.1016/j.jgo.2017.07.010
PubMed: 28807738

Affiliations:

Afrique du Sud, Australie, Belgique, Chypre (pays), Espagne, France, Russie, République tchèque
Bohême centrale, Catalogne, Moravie
Barcelone, Brno, Prague

Le document en format XML

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Serveur d'exploration sur les relations entre la France et l'Australie

Observed benefit and safety of aflibercept in elderly patients with metastatic colorectal cancer: An age-based analysis from the randomized placebo-controlled phase III VELOUR trial.

Observed benefit and safety of aflibercept in elderly patients with metastatic colorectal cancer: An age-based analysis from the randomized placebo-controlled phase III VELOUR trial.

Source :

Abstract

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	Serveur d'exploration sur les relations entre la France et l'Australie
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